Beyond the chromosome: the prevalence of unique extra-chromosomal bacteriophages with integrated virulence genes in pathogenic Staphylococcus aureus.

In Staphylococcus aureus, the disease impact of chromosomally integrated prophages on virulence is well described. However, the existence of extra-chromosomal prophages, both plasmidial and episomal, remains obscure. Despite the recent explosion in bacterial and bacteriophage genomic sequencing, stu...

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Bibliographic Details
Main Authors: Bryan Utter, Douglas R Deutsch, Raymond Schuch, Benjamin Y Winer, Kathleen Verratti, Kim Bishop-Lilly, Shanmuga Sozhamannan, Vincent A Fischetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4070920?pdf=render