Cellular and molecular mechanisms of muscle atrophy
Skeletal muscle is a plastic organ that is maintained by multiple pathways regulating cell and protein turnover. During muscle atrophy, proteolytic systems are activated, and contractile proteins and organelles are removed, resulting in the shrinkage of muscle fibers. Excessive loss of muscle mass i...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2013-01-01
|
Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/6/1/25 |