Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics

Nitric oxide is a volatile free radical second messenger with a large number of biological effects. Here Eroglu et al. develop genetically encoded fluorescent biosensors for nitric oxide and use them to visualise subcellular nitric oxide dynamics in single cells.

Bibliographic Details
Main Authors: Emrah Eroglu, Benjamin Gottschalk, Suphachai Charoensin, Sandra Blass, Helmut Bischof, Rene Rost, Corina T. Madreiter-Sokolowski, Brigitte Pelzmann, Eva Bernhart, Wolfgang Sattler, Seth Hallström, Tadeusz Malinski, Markus Waldeck-Weiermair, Wolfgang F. Graier, Roland Malli
Format: Article
Language:English
Published: Nature Publishing Group 2016-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10623