Mechanisms of foot-and-mouth disease virus tropism inferred from differential tissue gene expression.

Foot-and-mouth disease virus (FMDV) targets specific tissues for primary infection, secondary high-titer replication (e.g. foot and mouth where it causes typical vesicular lesions) and long-term persistence at some primary replication sites. Although integrin αVβ6 receptor has been identified as pri...

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Bibliographic Details
Main Authors: James J Zhu, Jonathan Arzt, Michael C Puckette, George R Smoliga, Juan M Pacheco, Luis L Rodriguez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23724025/pdf/?tool=EBI