Progress towards an inducible, replication-proficient transposon delivery vector for Chlamydia trachomatis [version 1; peer review: 2 approved]

Background Genetic systems have been developed for Chlamydia but the extremely low transformation frequency remains a significant bottleneck.  Our goal is to develop a self-replicating transposon delivery vector for C. trachomatis which can be expanded prior to transposase induction. Methods We made...

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Bibliographic Details
Main Authors: Rachel J. Skilton, Colette O'Neill, Nicholas R. Thomson, David J. Lampe, Ian N. Clarke
Format: Article
Language:English
Published: Wellcome 2021-04-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/6-82/v1