Molecular evolutionary and structural analysis of familial exudative vitreoretinopathy associated FZD4 gene

Abstract Background Frizzled family members belong to G-protein coupled receptors and encode proteins accountable for cell signal transduction, cell proliferation and cell death. Members of Frizzled receptor family are considered to have critical roles in causing various forms of cancer, cardiac hyp...

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Bibliographic Details
Main Authors: Suman Seemab, Nashaiman Pervaiz, Rabail Zehra, Saneela Anwar, Yiming Bao, Amir Ali Abbasi
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Evolutionary Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12862-019-1400-9