Chromosomal rearrangements and protein globularity changes in Mycobacterium tuberculosis isolates from cerebrospinal fluid

Background Meningitis is a major cause of mortality in tuberculosis (TB). It is not clear what factors promote central nervous system invasion and pathology but it has been reported that certain strains of Mycobacterium tuberculosis (Mtb) might have genetic traits associated with neurotropism. Metho...

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Bibliographic Details
Main Authors: Seow Hoon Saw, Joon Liang Tan, Xin Yue Chan, Kok Gan Chan, Yun Fong Ngeow
Format: Article
Language:English
Published: PeerJ Inc. 2016-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/2484.pdf