The effect of size, charge, and peptide ligand length on kidney targeting by small, organic nanoparticles

Abstract Chronic kidney disease (CKD) affects 15% of the US adult population. However, most clinically available drugs for CKD show low bioavailability to the kidneys and non‐specific uptake by other organs which results in adverse side effects. Hence, a targeted, drug delivery strategy to enhance k...

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Bibliographic Details
Main Authors: Yi Huang, Kairui Jiang, Xuting Zhang, Eun Ji Chung
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10173