The effect of size, charge, and peptide ligand length on kidney targeting by small, organic nanoparticles
Abstract Chronic kidney disease (CKD) affects 15% of the US adult population. However, most clinically available drugs for CKD show low bioavailability to the kidneys and non‐specific uptake by other organs which results in adverse side effects. Hence, a targeted, drug delivery strategy to enhance k...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-09-01
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Series: | Bioengineering & Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/btm2.10173 |