Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury

Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury

<p>Abstract</p> <p>Background</p> <p>Phosphodiesterase-5 inhibition with sildenafil has been used to treat severe pulmonary hypertension and bronchopulmonary dysplasia (BPD), a chronic lung disease in very preterm infants who were mechanically ventilated for respiratory...

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Bibliographic Details
Main Authors: Boersma Hester, Laghmani El Houari, Walther Frans J, de Visser Yvonne P, van der Laarse Arnoud, Wagenaar Gerry TM
Format: Article
Language:English
Published: BMC 2009-04-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/30

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