Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury

<p>Abstract</p> <p>Background</p> <p>Phosphodiesterase-5 inhibition with sildenafil has been used to treat severe pulmonary hypertension and bronchopulmonary dysplasia (BPD), a chronic lung disease in very preterm infants who were mechanically ventilated for respiratory...

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Bibliographic Details
Main Authors: Boersma Hester, Laghmani El Houari, Walther Frans J, de Visser Yvonne P, van der Laarse Arnoud, Wagenaar Gerry TM
Format: Article
Language:English
Published: BMC 2009-04-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/30