Role of cyclic nucleotide-dependent actin cytoskeletal dynamics:Ca(2+)](i) and force suppression in forskolin-pretreated porcine coronary arteries.

Initiation of force generation during vascular smooth muscle contraction involves a rise in intracellular calcium ([Ca(2+)]i) and phosphorylation of myosin light chains (MLC). However, reversal of these two processes alone does not account for the force inhibition that occurs during relaxation or in...

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Bibliographic Details
Main Authors: Kyle M Hocking, Franz J Baudenbacher, Gowthami Putumbaka, Sneha Venkatraman, Joyce Cheung-Flynn, Colleen M Brophy, Padmini Komalavilas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3625185?pdf=render