Activation of PI3K/AKT and ERK MAPK signal pathways is required for the induction of lytic cycle replication of Kaposi's Sarcoma-associated herpesvirus by herpes simplex virus type 1

<p>Abstract</p> <p>Background</p> <p>Kaposi's sarcoma-associated herpesvirus (KSHV) is causally linked to several acquired immunodeficiency syndrome-related malignancies, including Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and a subset of multicen...

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Bibliographic Details
Main Authors: Lv Zhigang, Yan Qin, Ma Xinting, Fan Weifei, Feng Ninghan, Qin Di, Zeng Yi, Zhu Jianzhong, Lu Chun
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Microbiology
Online Access:http://www.biomedcentral.com/1471-2180/11/240