BK channels regulate spontaneous action potential rhythmicity in the suprachiasmatic nucleus.

BACKGROUND: Circadian ( approximately 24 hr) rhythms are generated by the central pacemaker localized to the suprachiasmatic nucleus (SCN) of the hypothalamus. Although the basis for intrinsic rhythmicity is generally understood to rely on transcription factors encoded by "clock genes", le...

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Bibliographic Details
Main Authors: Jack Kent, Andrea L Meredith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2586654?pdf=render