KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc

KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc

Abstract Background Cancer cells maintain energy metabolism mainly by glycolysis, even under sufficient oxygen conditions. It gives cancer cells better growth advantages under complicated internal environment. KPNA2 is a novel oncogene that has received much attention in recent years, but the exact...

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Bibliographic Details
Main Authors: Jie Li, Qian Liu, Zihao Liu, Qian Xia, Zihao Zhang, Rui Zhang, Taihong Gao, Guangyan Gu, Yanan Wang, Dan Wang, Xiuyang Chen, Yihang Yang, Dong He, Tao Xin
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
KPNA2
Warburg effect
c-myc
Glioma
E2F1
Online Access:http://link.springer.com/article/10.1186/s13046-018-0861-9

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http://link.springer.com/article/10.1186/s13046-018-0861-9

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