The ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule pathway, stabilizes Tex19.1 during spermatogenesis.

The ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule pathway, stabilizes Tex19.1 during spermatogenesis.

Ubiquitin E3 ligases target their substrates for ubiquitination, leading to proteasome-mediated degradation or altered biochemical properties. The ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule proteolytic pathway, recognizes proteins with N-terminal destabilizing residues and p...

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Bibliographic Details
Main Authors: Fang Yang, Yong Cheng, Jee Young An, Yong Tae Kwon, Sigrid Eckardt, N Adrian Leu, K John McLaughlin, Peijing Jeremy Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2982839?pdf=render

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http://europepmc.org/articles/PMC2982839?pdf=render

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