mRNA-Driven Generation of Transgene-Free Neural Stem Cells from Human Urine-Derived Cells

mRNA-Driven Generation of Transgene-Free Neural Stem Cells from Human Urine-Derived Cells

Human neural stem cells (NSCs) hold enormous promise for neurological disorders, typically requiring their expandable and differentiable properties for regeneration of damaged neural tissues. Despite the therapeutic potential of induced NSCs (iNSCs), a major challenge for clinical feasibility is the...

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Bibliographic Details
Main Authors: Phil Jun Kang, Daryeon Son, Tae Hee Ko, Wonjun Hong, Wonjin Yun, Jihoon Jang, Jong-Il Choi, Gwonhwa Song, Jangbo Lee, In Yong Kim, Seungkwon You
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
induced neural stem cells (iNSCs)
self-replicative mRNA
direct conversion
reprogramming
small molecules
neurological diseases
Online Access:https://www.mdpi.com/2073-4409/8/9/1043

Internet

https://www.mdpi.com/2073-4409/8/9/1043

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