Prostaglandins in Cancer Cell Adhesion, Migration, and Invasion

Prostaglandins exert a profound influence over the adhesive, migratory, and invasive behavior of cells during the development and progression of cancer. Cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) are upregulated in inflammation and cancer. This results in the produ...

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Bibliographic Details
Main Authors: David G. Menter, Raymond N. DuBois
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2012/723419