An Evidenced-Based Scale of Disease Severity following Human Challenge with Enteroxigenic Escherichia coli.

An Evidenced-Based Scale of Disease Severity following Human Challenge with Enteroxigenic Escherichia coli.

BACKGROUND:Experimental human challenge models have played a major role in enhancing our understanding of infectious diseases. Primary outcomes have typically utilized overly simplistic outcomes that fail to entirely account for complex illness syndromes. We sought to characterize clinical outcomes...

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Bibliographic Details
Main Authors: Chad K Porter, Mark S Riddle, Ashley N Alcala, David A Sack, Clayton Harro, Subhra Chakraborty, Ramiro L Gutierrez, Stephen J Savarino, Michael Darsley, Robin McKenzie, Barbara DeNearing, Hans Steinsland, David R Tribble, A Louis Bourgeois
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4777366?pdf=render

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http://europepmc.org/articles/PMC4777366?pdf=render

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