The i-Motif as a Molecular Target: More than a Complementary DNA Secondary Structure
Stretches of cytosine-rich DNA are capable of adopting a dynamic secondary structure, the i-motif. When within promoter regions, the i-motif has the potential to act as a molecular switch for controlling gene expression. However, i-motif structures in genomic areas of repetitive nucleotide sequences...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/14/2/96 |