Frequency of CCR5 Delta-32 Mutation in Human Immunodeficiency Virus (HIV)-seropositive and HIV-exposed Seronegative Individuals and in General Population of Medellin, Colombia

Frequency of CCR5 Delta-32 Mutation in Human Immunodeficiency Virus (HIV)-seropositive and HIV-exposed Seronegative Individuals and in General Population of Medellin, Colombia

Repeated exposure to human immunodeficiency virus (HIV) does not always result in seroconversion. Modifications in coreceptors for HIV entrance to target cells are one of the factors that block the infection. We studied the frequency of Delta-32 mutation in ccr5 gene in Medellin, Colombia. Two hundr...

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Bibliographic Details
Main Authors: Francisco J Díaz, Jorge A Vega, Pablo J Patiño, Gabriel Bedoya, Jorge Nagles, Cecilia Villegas, Rodrigo Vesga, Maria T Rugeles
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2000-04-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
CCR5
Delta-32 mutation
human immunodeficiency virus (HIV) infection
exposed seronegative
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000200018

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000200018

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