Chronic Inhibition of Mitochondrial Dihydrolipoamide Dehydrogenase (DLDH) as an Approach to Managing Diabetic Oxidative Stress

Chronic Inhibition of Mitochondrial Dihydrolipoamide Dehydrogenase (DLDH) as an Approach to Managing Diabetic Oxidative Stress

Mitochondrial dihydrolipoamide dehydrogenase (DLDH) is a redox enzyme involved in decarboxylation of pyruvate to form acetyl-CoA during the cascade of glucose metabolism and mitochondrial adenine triphosphate (ATP) production. Depending on physiological or pathophysiological conditions, DLDH can eit...

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Bibliographic Details
Main Authors: Xiaojuan Yang, Jing Song, Liang-Jun Yan
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Antioxidants
Subjects:
diabetes mellitus
dihydrolipoamide dehydrogenase
mitochondria
oxidative stress
reactive oxygen species
Online Access:https://www.mdpi.com/2076-3921/8/2/32

Internet

https://www.mdpi.com/2076-3921/8/2/32

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