An immunohistochemical prostate cell identification key indicates that aging shifts procollagen 1A1 production from myofibroblasts to fibroblasts in dogs prone to prostate-related urinary dysfunction.

An immunohistochemical prostate cell identification key indicates that aging shifts procollagen 1A1 production from myofibroblasts to fibroblasts in dogs prone to prostate-related urinary dysfunction.

<h4>Background</h4>The identity and spatial distribution of prostatic cell types has been determined in humans but not in dogs, even though aging- and prostate-related voiding disorders are common in both species and mechanistic factors, such as prostatic collagen accumulation, appear to...

Full description

Bibliographic Details
Main Authors: Hannah Ruetten, Clara Cole, Marlyse Wehber, Kyle A Wegner, Nicholas M Girardi, Nelson T Peterson, Brandon R Scharpf, Michael F Romero, Michael W Wood, Sara A Colopy, Dale E Bjorling, Chad M Vezina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232564

Internet

https://doi.org/10.1371/journal.pone.0232564

Similar Items