α-Synuclein overexpression increases dopamine toxicity in BE(2)-M17 cells

<p>Abstract</p> <p>Background</p> <p>Oxidative stress has been proposed to be involved in the pathogenesis of Parkinson's disease (PD). A plausible source of oxidative stress in nigral dopaminergic neurons is the redox reactions that specifically involve dopamine a...

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Bibliographic Details
Main Authors: Miller David W, Maric Dragan, Greggio Elisa, Bisaglia Marco, Cookson Mark R, Bubacco Luigi
Format: Article
Language:English
Published: BMC 2010-03-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/11/41