Homozygosity for the SCN10A Polymorphism rs6795970 Is Associated With Hypoalgesic Inflammatory Bowel Disease Phenotype

Homozygosity for the SCN10A Polymorphism rs6795970 Is Associated With Hypoalgesic Inflammatory Bowel Disease Phenotype

Background: Hypoalgesic inflammatory bowel disease (IBD), a condition in which patients with active disease do not perceive and/or report abdominal pain, is associated with serious complications and there is a lack of cost-effective, reliable diagnostic methods to identify “at-risk” patients. The vo...

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Bibliographic Details
Main Authors: Eugene Gonzalez-Lopez, Yuka Imamura Kawasawa, Vonn Walter, Lijun Zhang, Walter A. Koltun, Xuemei Huang, Kent E. Vrana, Matthew D. Coates
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Medicine
Subjects:
genetic polymorphism
inflammatory bowel disease
voltage-gated sodium channels
Nav1.8
SCN10A
hypoalgesia
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2018.00324/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2018.00324/full

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