CXCL1/CXCR2 signaling in pathological pain: Role in peripheral and central sensitization

Pathological pain conditions can be triggered after peripheral nerve injury and/or inflammation. It is associated with plasticity of nociceptive pathway in which pain is prolonged even after healing of the injured tissue. Generally combinations of analgesic drugs are not sufficient to achieve select...

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Bibliographic Details
Main Authors: Rangel L. Silva, Alexandre H. Lopes, Rafaela M. Guimarães, Thiago M. Cunha
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117301286