Review: Therapeutic implications of hepatitis C virus resistance to antiviral drugs

Treatment of chronic hepatitis C is currently based on a combination of pegylated interferon-α and ribavirin. Neither drug exerts direct selective pressure on viral functions, meaning that interferon-α/ribavirin treatment failure is not due to selection of interferon-α- or ribavirin-resistant viral...

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Bibliographic Details
Main Author: Jean-Michel Pawlotsky
Format: Article
Language:English
Published: SAGE Publishing 2009-07-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756283X09336045