Probiotic-derived polyphosphate enhances the epithelial barrier function and maintains intestinal homeostasis through integrin-p38 MAPK pathway.

Probiotics exhibit beneficial effects on human health, particularly in the maintenance of intestinal homeostasis in a complex manner notwithstanding the diversity of an intestinal flora between individuals. Thus, it is highly probable that some common molecules secreted by probiotic and/or commensal...

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Bibliographic Details
Main Authors: Shuichi Segawa, Mikihiro Fujiya, Hiroaki Konishi, Nobuhiro Ueno, Naoyuki Kobayashi, Tatsuro Shigyo, Yutaka Kohgo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3156119?pdf=render