A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols

Catechol dehydroxylation is a central chemical transformation in the gut microbial metabolism of plant- and host-derived small molecules. However, the molecular basis for this transformation and its distribution among gut microorganisms are poorly understood. Here, we characterize a molybdenum-depen...

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Bibliographic Details
Main Authors: Vayu Maini Rekdal, Paola Nol Bernadino, Michael U Luescher, Sina Kiamehr, Chip Le, Jordan E Bisanz, Peter J Turnbaugh, Elizabeth N Bess, Emily P Balskus
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/50845