Farnesyl transferase inhibitors induce extended remissions in transgenic mice with mature B cell lymphomas
<p>Abstract</p> <p>Background</p> <p>We have used a mouse model based on overexpression of <it>c-Myc </it>in B cells genetically engineered to be self-reactive to test the hypothesis that farnesyl transferase inhibitors (FTIs) can effectively treat mature B...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-05-01
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| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/7/1/39 |