Potential for Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy for Lung Cancer with 4-Dimensional Robust Optimization

Potential for Improvements in Robustness and Optimality of Intensity-Modulated Proton Therapy for Lung Cancer with 4-Dimensional Robust Optimization

Background: Major challenges in the application of intensity-modulated proton therapy (IMPT) for lung cancer patients include the uncertainties associated with breathing motion, its mitigation and its consideration in IMPT optimization. The primary objective of this research was to evaluate the pote...

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Bibliographic Details
Main Authors: Shuaiping Ge, Xiaochun Wang, Zhongxing Liao, Lifei Zhang, Narayan Sahoo, Jinzhong Yang, Fada Guan, Radhe Mohan
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cancers
Subjects:
proton therapy
4-dimensional robust optimization
motion management
uncertainties
lung cancer
Online Access:http://www.mdpi.com/2072-6694/11/1/35

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http://www.mdpi.com/2072-6694/11/1/35

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