An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2

An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2

Tomer Meirson, Abraham O Samson, Hava Gil-Henn Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel Abstract: The non-receptor tyrosine kinase proline-rich tyrosine kinase 2 (Pyk2) is a critical mediator of signaling from cell surface growth factor and adhesion receptors to cell...

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Bibliographic Details
Main Authors: Meirson T, Samson AO, Gil-Henn H
Format: Article
Language:English
Published: Dove Medical Press 2017-05-01
Series:Drug Design, Development and Therapy
Subjects:
Pyk2
virtual screen
efficiency metrics
molecular dynamics
Online Access:https://www.dovepress.com/an-in-silico-high-throughput-screen-identifies-potential-selective-inh-peer-reviewed-article-DDDT

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https://www.dovepress.com/an-in-silico-high-throughput-screen-identifies-potential-selective-inh-peer-reviewed-article-DDDT

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