Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages

The origins of lineage correlations and heterogeneity in division and apoptosis times among single cells are incompletely understood. Here, a new lineage tracking data analysis approach reveals that circadian oscillations may underlie cell fate control and explain the observed correlation structures...

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Bibliographic Details
Main Authors: Shaon Chakrabarti, Andrew L. Paek, Jose Reyes, Kathleen A. Lasick, Galit Lahav, Franziska Michor
Format: Article
Language:English
Published: Nature Publishing Group 2018-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07788-5