Methylenetetrahydrofolate reductase gene polymorphism, global DNA methylation and blood pressure: a population based study from North India

Abstract Background Hypertension is a complex disorder affected by gene-environment interactions. Methylenetetrahydrofolate reductase (MTHFR) gene is one of the genes in One Carbon Metabolic (OCM) pathway that affects both blood pressure and epigenetic phenomenon. MTHFR C677T gene polymorphism leads...

Full description

Bibliographic Details
Main Authors: Suniti Yadav, Imnameren Longkumer, Shipra Joshi, Kallur Nava Saraswathy
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Medical Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12920-021-00895-1