The relationship between CD204 M2-polarized tumour-associated macrophages (TAMs), tumour-infiltrating lymphocytes (TILs), and microglial activation in glioblastoma microenvironment: a novel immune checkpoint receptor target

The relationship between CD204 M2-polarized tumour-associated macrophages (TAMs), tumour-infiltrating lymphocytes (TILs), and microglial activation in glioblastoma microenvironment: a novel immune checkpoint receptor target

Abstract Background Tumour associated macrophages (TAMs) and tumour infiltrating lymphocytes (TILs) are considered dominant cells in glioblastoma microenvironment. Aim The purpose of this study was to assess the expression of CD204+ M2-polarized TAMs in glioblastomas and their relationship with CD4+...

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Bibliographic Details
Main Authors: Maher Kurdi, Badrah Alghamdi, Nadeem Shafique Butt, Saleh Baeesa
Format: Article
Language:English
Published: Springer 2021-08-01
Series:Discover Oncology
Subjects:
Glioblastoma
Tumour associated macrophages
CD204
Tumour infiltrating lymphocytes
Microglial activation
Immune check point receptors
Online Access:https://doi.org/10.1007/s12672-021-00423-8

Internet

https://doi.org/10.1007/s12672-021-00423-8

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