The Analgesic Effect of Venlafaxine and Its Mechanism on Oxaliplatin-Induced Neuropathic Pain in Mice

The Analgesic Effect of Venlafaxine and Its Mechanism on Oxaliplatin-Induced Neuropathic Pain in Mice

The analgesic effect of venlafaxine (VLX), which is a selective serotonin and noradrenaline reuptake inhibitor (SNRI), has been observed on oxaliplatin-induced neuropathic pain in mice. Significant allodynia was shown after oxaliplatin treatment (6 mg/kg, i.p.); acetone and von Frey hair tests were...

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Bibliographic Details
Main Authors: Daxian Li, Ji Hwan Lee, Chang Won Choi, Jaihwan Kim, Sun Kwang Kim, Woojin Kim
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
chemotherapy-induced neuropathic pain
noradrenaline
oxaliplatin
serotonin
venlafaxine
Online Access:https://www.mdpi.com/1422-0067/20/7/1652

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https://www.mdpi.com/1422-0067/20/7/1652

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