A Tandem Repeat in Decay Accelerating Factor 1 Is Associated with Severity of Murine Mercury-Induced Autoimmunity

Decay accelerating factor (DAF), a complement-regulatory protein, protects cells from bystander complement-mediated lysis and negatively regulates T cells. Reduced expression of DAF occurs in several systemic autoimmune diseases including systemic lupus erythematosus, and DAF deficiency exacerbates...

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Bibliographic Details
Main Authors: David M. Cauvi, Rodney Gabriel, Dwight H. Kono, Per Hultman, K. Michael Pollard
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Autoimmune Diseases
Online Access:http://dx.doi.org/10.1155/2014/260613