Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast

<p>Abstract</p> <p>Background</p> <p><it>N</it>-hydroxylated base analogs, such as 6-hydroxylaminopurine (HAP) and 2-amino-6-hydroxylaminopurine (AHA), are strong mutagens in various organisms due to their ambiguous base-pairing properties. The systems prote...

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Bibliographic Details
Main Authors: Kozmin Stanislav G, Stepchenkova Elena I, Alenin Vladimir V, Pavlov Youri I
Format: Article
Language:English
Published: BMC 2005-06-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/6/31