Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis

Epigenetics is often defined as the study of heritable changes in gene expression or chromosome stability that don’t alter the underlying DNA sequence. Epigenetic changes are established through multiple mechanisms that include DNA methylation, non-coding RNAs and the covalent modification of specif...

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Bibliographic Details
Main Authors: Thomas A. Milne, Erica Ballabio
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Cancers
Subjects:
MLL
Online Access:http://www.mdpi.com/2072-6694/4/3/904