Alternative syntheses of 3-hydroxy-17-bromo-16,17-secoestra-1,3,5(10)-triene-16-nitrile and crystallographic studies of two intermediates

Abstract: Starting from estrone 3-benzyloxy-17-hydroxy-16,17-secoestra-1,3,5(10)-triene- 16-nitrile (1) was synthesized in several synthetic steps. This compound was the key intermediate in the syntheses of other 17-substituted-16,17-secoestrone derivatives. Among them 3-hydroxy-17-bromo-16,17-secoe...

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Bibliographic Details
Main Authors: Jovanović-Šanta Suzana S., Đurendić Evgenija A., Lazar Dušan V., Stanković Slobodanka M.
Format: Article
Language:English
Published: Serbian Chemical Society 2005-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2005/0352-51390504577J.pdf