Internalization mechanisms of the epidermal growth factor receptor after activation with different ligands.

Internalization mechanisms of the epidermal growth factor receptor after activation with different ligands.

The epidermal growth factor receptor (EGFR) regulates normal growth and differentiation, but dysregulation of the receptor or one of the EGFR ligands is involved in the pathogenesis of many cancers. There are eight ligands for EGFR, however most of the research into trafficking of the receptor after...

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Bibliographic Details
Main Authors: Lasse Henriksen, Michael Vibo Grandal, Stine Louise Jeppe Knudsen, Bo van Deurs, Lene Melsæther Grøvdal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3589378?pdf=render

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http://europepmc.org/articles/PMC3589378?pdf=render

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