Detection of HPV and Human Chromosome Sites by Dual-Color Fluorescence In Situ Hybridization Reveals Recurrent HPV Integration Sites and Heterogeneity in Cervical Cancer

Detection of HPV and Human Chromosome Sites by Dual-Color Fluorescence In Situ Hybridization Reveals Recurrent HPV Integration Sites and Heterogeneity in Cervical Cancer

Human papillomavirus (HPV) integration in the human genome is suggested to be an important cause of cervical cancer. With the development of sequencing technologies, an increasing number of integration “hotspots” have been identified. However, this HPV integration information was derived from analys...

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Bibliographic Details
Main Authors: Jinfeng Xiong, Jing Cheng, Hui Shen, Ci Ren, Liming Wang, Chun Gao, Tong Zhu, Xiaomin Li, Wencheng Ding, Da Zhu, Hui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
human papillomavirus
HPV integration
FISH
cervical cancer
site-specific
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.734758/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.734758/full

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