The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria

The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria

Abstract Background Recent genome wide analysis studies have identified a strong association between single nucleotide variations within the human ATP2B4 gene and susceptibility to severe malaria. The ATP2B4 gene encodes the plasma membrane calcium ATPase 4 (PMCA4), which is responsible for controll...

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Bibliographic Details
Main Authors: Ana Villegas-Mendez, Nicholas Stafford, Michael J. Haley, Normalita Eka Pravitasari, Florence Baudoin, Adnan Ali, Puji Budi Setia Asih, Josephine E. Siregar, Esther Baena, Din Syafruddin, Kevin N. Couper, Delvac Oceandy
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Malaria Journal
Subjects:
PMCA4
Malaria
Knockout mice
Plasmodium
Cerebral malaria
Red blood cell
Online Access:https://doi.org/10.1186/s12936-021-03832-w

Internet

https://doi.org/10.1186/s12936-021-03832-w

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