A novel mice model of acute flares in osteoarthritis elicited by intra-articular injection of cultured mast cells

Abstract Purpose Mast cells are multifunctional in osteoarthritis (OA), and infiltration of activated mast cells likely contributes to disease severity and progression. However, the detailed mechanisms of action are unclear. The purpose of this study was to elucidate the role of mast cell infiltrati...

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Bibliographic Details
Main Authors: Junpei Dan, Masashi Izumi, Hiroko Habuchi, Osami Habuchi, Shogo Takaya, Yusuke Kasai, Ryuzo Hayashi, Koji Aso, Takahiro Ushida, Masahiko Ikeuchi
Format: Article
Language:English
Published: SpringerOpen 2021-09-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:https://doi.org/10.1186/s40634-021-00391-6