Protease activity of PprI facilitates DNA damage response: Mn2+-dependence and substrate sequence-specificity of the proteolytic reaction.

Protease activity of PprI facilitates DNA damage response: Mn2+-dependence and substrate sequence-specificity of the proteolytic reaction.

The extremophilic bacterium Deinococcus radiodurans exhibits an extraordinary resistance to ionizing radiation. Previous studies established that a protein named PprI, which exists only in the Deinococcus-Thermus family, acts as a general switch to orchestrate the expression of a number of DNA damag...

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Bibliographic Details
Main Authors: Yunguang Wang, Qiang Xu, Huiming Lu, Lin Lin, Liangyan Wang, Hong Xu, Xianyan Cui, Hui Zhang, Tingting Li, Yuejin Hua
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4374696?pdf=render

Internet

http://europepmc.org/articles/PMC4374696?pdf=render

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