Divergent Roles of Kupffer Cell TLR2/3 Signaling in Alcoholic Liver Disease and the Protective Role of EGCGSummary

Divergent Roles of Kupffer Cell TLR2/3 Signaling in Alcoholic Liver Disease and the Protective Role of EGCGSummary

Background & Aims: Toll-like receptor 2 (TLR2) and TLR3 regulate hepatic immunity under pathological conditions, but their functions and potential drug targets in alcoholic liver disease (ALD) remain poorly understood. Methods: ALD-associated liver injury were induced in TLR2 knockout (TLR2–/–),...

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Main Authors: Pingping Luo, Fei Wang, Nai-Kei Wong, Yi Lv, Xinxin Li, Mianhuan Li, George L. Tipoe, Kwok-Fai So, Aimin Xu, Shuaiyin Chen, Jia Xiao, Hua Wang
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19301201

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http://www.sciencedirect.com/science/article/pii/S2352345X19301201

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