Analysis of human protein replacement stable cell lines established using snoMEN-PR vector.
The study of the function of many human proteins is often hampered by technical limitations, such as cytotoxicity and phenotypes that result from overexpression of the protein of interest together with the endogenous version. Here we present the snoMEN (snoRNA Modulator of gene ExpressioN) vector te...
Main Authors: | Motoharu Ono, Kayo Yamada, Akinori Endo, Fabio Avolio, Angus I Lamond |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3636044?pdf=render |
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