Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors.

Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors.

Almost all prostate cancers respond to androgen deprivation treatment but many recur. We postulated that risk of hormone escape--frequency and delay--are influenced by hormone therapy modalities. More, hormone therapies induce crucial biological changes involving androgen receptors; some might be ta...

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Bibliographic Details
Main Authors: Charlotte Guyader, Jocelyn Céraline, Eléonore Gravier, Aurélie Morin, Sandrine Michel, Eva Erdmann, Gonzague de Pinieux, Florence Cabon, Jean-Pierre Bergerat, Marie-France Poupon, Stéphane Oudard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3412862?pdf=render

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http://europepmc.org/articles/PMC3412862?pdf=render

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