Major role of adipocyte prostaglandin E2 in lipolysis-induced macrophage recruitment[S]

Obesity induces accumulation of adipose tissue macrophages (ATMs), which contribute to both local and systemic inflammation and modulate insulin sensitivity. Adipocyte lipolysis during fasting and weight loss also leads to ATM accumulation, but without proinflammatory activation suggesting distinct...

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Bibliographic Details
Main Authors: Xiaoqian Hu, Vincenza Cifarelli, Shishuo Sun, Ondrej Kuda, Nada A. Abumrad, Xiong Su
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520354213