Major role of adipocyte prostaglandin E2 in lipolysis-induced macrophage recruitment[S]
Obesity induces accumulation of adipose tissue macrophages (ATMs), which contribute to both local and systemic inflammation and modulate insulin sensitivity. Adipocyte lipolysis during fasting and weight loss also leads to ATM accumulation, but without proinflammatory activation suggesting distinct...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-04-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520354213 |