Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism

Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism

Summary: Cold-induced thermogenesis in endotherms demands adaptive thermogenesis fueled by mitochondrial respiration and Ucp1-mediated uncoupling in multilocular brown adipocytes (BAs). However, dietary regulation of thermogenesis in BAs isn’t fully understood. Here, we describe that the deficiency...

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Bibliographic Details
Main Authors: Esther Paulo, Yun Zhang, Ruchi Masand, Tony L. Huynh, Youngho Seo, Danielle L. Swaney, Margaret Soucheray, Erica Stevenson, David Jimenez-Morales, Nevan J. Krogan, Biao Wang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
brown adipocyte
thermogenesis
ATF4
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721011955

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http://www.sciencedirect.com/science/article/pii/S2211124721011955

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