Temporal Expression of Mutant LRRK2 in Adult Rats Impairs Dopamine Reuptake

<p>Parkinson's disease (PD) results from progressive degeneration of dopaminergic neurons. Most PD cases are sporadic, but some have pathogenic mutation in the individual genes. Mutation of the <i>leucine-rich repeat kinase-2</i> (<i>LRRK2</i>) gene is associated w...

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Bibliographic Details
Main Author: Hongxia Zhou, Cao Huang, Jianbin Tong, Weimin C Hong, Yong-Jian Liu, Xu-Gang Xia
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v07p0753.htm